Angela Little was born in Albertville, Alabama. Girl was the cheerleader in high school and she was also the homecoming queen at Douglas high school in Alabama. She was given a nickname "Little Marilyn" by the founder and publisher of Playboy Magazine. She has acted in many movies like Walk Hard with John C. Reilly, American Pie: Band Camp, Rush Hour 2 and My Boss's Daughter. She has also given guest appearance in many television series like Cold Case, CSI, Nip/Tuck, Monk, The Mullets, Charmed, Malcolm in the Middle, Reno 911 and the soap opera The Bold and the Beautiful. She has also played a role in the short lived television series Buddy Faro. She also hosted the show Wild on the Windy City that was aired on E! Channel.

She was the St. Paul Girl for 2000 and she was the second Playmate national spokes models for the beer brand after Jaime Bergman. Apart from acting and hosting shows she has also choreographed and performed cabaret style dance reviews for casino venues.